:root {
  --ink: #14212b;
  --muted: #5a6873;
  --soft: #edf4f6;
  --line: #d9e3e7;
  --paper: #fbfcfb;
  --white: #ffffff;
  --teal: #0b6c75;
  --blue: #1f5f9a;
  --green: #658662;
  --sand: #e7dfd1;
  --shadow: 0 24px 70px rgba(20, 33, 43, 0.12);
  --serif: "Source Serif 4", Georgia, serif;
  --sans: Inter, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;
}

* {
  box-sizing: border-box;
}

html {
  scroll-behavior: smooth;
}

body {
  margin: 0;
  color: var(--ink);
  background: var(--paper);
  font-family: var(--sans);
  line-height: 1.6;
}

img {
  display: block;
  max-width: 100%;
}

.visually-hidden {
  position: absolute;
  overflow: hidden;
  width: 1px;
  height: 1px;
  margin: -1px;
  padding: 0;
  border: 0;
  clip: rect(0 0 0 0);
  white-space: nowrap;
}

a {
  color: inherit;
  text-decoration: none;
}

.site-header {
  position: sticky;
  top: 0;
  z-index: 20;
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 28px;
  min-height: 76px;
  padding: 14px clamp(20px, 4vw, 64px);
  border-bottom: 1px solid rgba(217, 227, 231, 0.82);
  background: rgba(251, 252, 251, 0.9);
  backdrop-filter: blur(18px);
}

.brand {
  display: inline-flex;
  align-items: center;
  gap: 12px;
  min-width: 236px;
}

.brand-mark {
  display: inline-flex;
  width: 42px;
  height: 42px;
  flex: 0 0 42px;
  align-items: center;
  justify-content: center;
  overflow: hidden;
  border-radius: 8px;
  background: #000;
}

.brand-mark img {
  width: 100%;
  height: 100%;
  object-fit: cover;
}

.brand strong,
.brand small {
  display: block;
}

.brand strong {
  font-size: 15px;
  line-height: 1.1;
}

.brand small {
  margin-top: 3px;
  color: var(--muted);
  font-size: 12px;
}

.site-nav {
  display: flex;
  flex-wrap: wrap;
  justify-content: flex-end;
  gap: 10px 22px;
  color: var(--muted);
  font-size: 14px;
  font-weight: 600;
}

.site-nav a {
  padding: 8px 0;
}

.site-nav a:hover {
  color: var(--teal);
}

.hero {
  display: grid;
  grid-template-columns: minmax(0, 0.92fr) minmax(440px, 1.08fr);
  gap: clamp(28px, 5vw, 76px);
  align-items: center;
  min-height: calc(100svh - 76px);
  padding: clamp(44px, 6vw, 86px) clamp(20px, 5vw, 76px) clamp(28px, 4vw, 56px);
}

.hero-copy {
  max-width: 760px;
}

.eyebrow,
.section-kicker {
  margin: 0 0 18px;
  color: var(--teal);
  font-size: 12px;
  font-weight: 800;
  letter-spacing: 0.12em;
  text-transform: uppercase;
}

.hero h1,
.section h2,
.site-footer h2 {
  margin: 0;
  font-family: var(--serif);
  font-weight: 700;
  letter-spacing: 0;
  line-height: 1.03;
}

.hero h1 {
  max-width: 760px;
  font-size: clamp(40px, 5.2vw, 66px);
}

.hero-lede {
  max-width: 660px;
  margin: 28px 0 0;
  color: var(--muted);
  font-size: clamp(17px, 1.45vw, 21px);
  line-height: 1.72;
}

.hero-actions {
  display: flex;
  flex-wrap: wrap;
  gap: 12px;
  margin-top: 36px;
}

.button {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  min-height: 48px;
  padding: 0 20px;
  border: 1px solid var(--ink);
  border-radius: 4px;
  font-size: 14px;
  font-weight: 800;
}

.button.primary {
  background: var(--ink);
  color: var(--white);
}

.button.secondary {
  background: transparent;
  color: var(--ink);
}

.hero-visual {
  position: relative;
  overflow: hidden;
  min-height: 420px;
  border-radius: 8px;
  box-shadow: var(--shadow);
  background: var(--soft);
}

.hero-visual img {
  width: 100%;
  height: clamp(420px, 64vh, 690px);
  object-fit: cover;
  object-position: center;
}

.research-hero-visual img {
  object-position: 48% 50%;
}

.hero-visual::after {
  position: absolute;
  inset: 0;
  content: "";
  background: linear-gradient(180deg, rgba(20, 33, 43, 0) 48%, rgba(20, 33, 43, 0.66) 100%);
}

.hero-caption {
  position: absolute;
  right: 22px;
  bottom: 22px;
  left: 22px;
  z-index: 2;
  display: flex;
  align-items: flex-end;
  justify-content: space-between;
  gap: 20px;
  color: var(--white);
}

.hero-caption span {
  font-size: 13px;
  font-weight: 700;
  text-transform: uppercase;
}

.hero-caption strong {
  max-width: 230px;
  text-align: right;
  font-size: 14px;
  line-height: 1.35;
}

.metrics {
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  border-top: 1px solid var(--line);
  border-bottom: 1px solid var(--line);
  background: var(--white);
}

.metrics div {
  min-height: 164px;
  padding: 30px clamp(20px, 4vw, 44px);
  border-right: 1px solid var(--line);
}

.metrics div:last-child {
  border-right: 0;
}

.metrics strong {
  display: block;
  color: var(--blue);
  font-family: var(--serif);
  font-size: clamp(38px, 4vw, 58px);
  line-height: 1;
}

.metrics span {
  display: block;
  max-width: 260px;
  margin-top: 14px;
  color: var(--muted);
  font-size: 14px;
  line-height: 1.5;
}

.home-summary {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 1px;
  border-top: 1px solid var(--line);
  border-bottom: 1px solid var(--line);
  background: var(--line);
}

.home-summary article {
  min-height: 330px;
  padding: clamp(26px, 4vw, 48px);
  background: var(--white);
}

.home-summary span,
.page-link-grid span {
  display: block;
  margin-bottom: 64px;
  color: var(--teal);
  font-family: var(--serif);
  font-size: 28px;
  font-weight: 700;
}

.home-summary h2,
.page-hero h1,
.page-link-grid h2 {
  margin: 0;
  font-family: var(--serif);
  font-weight: 700;
  letter-spacing: 0;
  line-height: 1.05;
}

.home-summary h2 {
  font-size: clamp(28px, 3vw, 42px);
}

.home-summary p {
  max-width: 440px;
  margin: 18px 0 0;
  color: var(--muted);
  font-size: 15px;
  line-height: 1.72;
}

.home-summary a,
.page-link-grid a {
  display: inline-flex;
  margin-top: 28px;
  color: var(--teal);
  font-size: 14px;
  font-weight: 800;
  border-bottom: 2px solid currentColor;
}

.home-photo-band {
  display: grid;
  grid-template-columns: 1.1fr 0.9fr 1fr;
  gap: 1px;
  background: var(--line);
}

.balanced-research-band {
  grid-template-columns: repeat(4, minmax(0, 1fr));
}

.home-photo-band img {
  width: 100%;
  height: clamp(280px, 34vw, 520px);
  object-fit: cover;
  object-position: center;
}

.research-photo-band {
  border-top: 1px solid var(--line);
}

.research-photo-band img {
  height: clamp(260px, 30vw, 430px);
  filter: saturate(0.94) contrast(1.04);
}

.research-photo-band img:first-child {
  background: #050607;
  object-position: center;
}

.research-photo-band img:nth-child(2) {
  object-position: center;
}

.research-photo-band img:nth-child(3) {
  object-position: 50% 50%;
}

.research-photo-band img:nth-child(4) {
  object-position: 55% 50%;
}

.page-hero {
  display: grid;
  grid-template-columns: minmax(0, 0.9fr) minmax(300px, 0.5fr);
  gap: clamp(28px, 6vw, 96px);
  align-items: end;
  padding: clamp(70px, 10vw, 138px) clamp(20px, 5vw, 76px);
  border-bottom: 1px solid var(--line);
  background: var(--paper);
}

.page-hero h1 {
  max-width: 880px;
  font-size: clamp(44px, 6.4vw, 88px);
}

.page-hero p {
  margin: 0;
  color: var(--muted);
  font-size: clamp(16px, 1.4vw, 20px);
  line-height: 1.82;
}

.page-link-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 1px;
  background: var(--line);
  border-bottom: 1px solid var(--line);
}

.page-link-grid article {
  min-height: 360px;
  padding: clamp(28px, 4vw, 54px);
  background: var(--white);
}

.page-link-grid h2 {
  font-size: clamp(30px, 4vw, 54px);
}

.page-link-grid p {
  max-width: 560px;
  margin: 20px 0 0;
  color: var(--muted);
  font-size: 16px;
  line-height: 1.76;
}

.research-page-hero h1 {
  max-width: 1040px;
}

.clinical-challenge-hero {
  display: grid;
  justify-items: center;
  padding: clamp(78px, 10vw, 148px) clamp(20px, 7vw, 120px);
  border-bottom: 1px solid var(--line);
  background: var(--paper);
  text-align: center;
}

.clinical-challenge-hero h1 {
  max-width: 1000px;
  margin: 16px 0 0;
  font-family: var(--serif);
  font-size: clamp(54px, 8vw, 112px);
  line-height: 0.98;
  letter-spacing: 0;
}

.clinical-challenge-hero p {
  max-width: 1060px;
  margin: clamp(28px, 4vw, 52px) 0 0;
  color: #344653;
  font-size: clamp(18px, 1.55vw, 24px);
  line-height: 1.78;
}

.clinical-question-row {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 1px;
  width: min(1120px, 100%);
  margin-top: clamp(34px, 5vw, 62px);
  border: 1px solid var(--line);
  background: var(--line);
  text-align: left;
}

.clinical-question-row span {
  min-height: 120px;
  padding: 24px;
  background: var(--white);
  color: var(--ink);
  font-family: var(--serif);
  font-size: clamp(20px, 2vw, 30px);
  font-weight: 700;
  line-height: 1.18;
}

.research-flow-section {
  padding: clamp(58px, 8vw, 112px) clamp(20px, 5vw, 76px);
  border-bottom: 1px solid var(--line);
  background: var(--white);
}

.research-flow-header {
  display: grid;
  grid-template-columns: minmax(0, 0.92fr) minmax(280px, 0.48fr);
  gap: clamp(28px, 6vw, 90px);
  align-items: end;
  margin-bottom: clamp(34px, 5vw, 64px);
}

.research-flow-header h2,
.research-topic-copy h2 {
  margin: 0;
  font-family: var(--serif);
  font-size: clamp(34px, 4.6vw, 66px);
  line-height: 1.05;
  letter-spacing: 0;
}

.research-flow-header p,
.research-topic-copy p {
  margin: 0;
  color: var(--muted);
  font-size: clamp(16px, 1.25vw, 18px);
  line-height: 1.82;
}

.vertical-research-flow {
  overflow: hidden;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: linear-gradient(180deg, #ffffff 0%, #f7faf9 100%);
}

.integrated-flow-grid {
  position: relative;
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: clamp(46px, 7vw, 112px);
  align-items: stretch;
  padding: clamp(24px, 4vw, 52px);
}

.integrated-topic {
  position: relative;
  z-index: 1;
  display: flex;
  min-width: 0;
  flex-direction: column;
  padding: clamp(24px, 3vw, 34px);
  border: 1px solid rgba(20, 33, 43, 0.12);
  border-radius: 8px;
  background: rgba(255, 255, 255, 0.88);
}

.integrated-topic.fna {
  box-shadow: inset 5px 0 0 rgba(11, 108, 117, 0.72);
}

.integrated-topic.surgery {
  box-shadow: inset 5px 0 0 rgba(31, 95, 154, 0.72);
}

.integrated-topic h3 {
  margin: 18px 0 0;
  font-family: var(--serif);
  font-size: clamp(30px, 3vw, 48px);
  line-height: 1.05;
  letter-spacing: 0;
}

.integrated-topic > p {
  margin: 22px 0 0;
  color: var(--muted);
  font-size: 15px;
  line-height: 1.76;
}

.scientific-question {
  margin-top: 26px;
  padding: 20px;
  border: 1px solid rgba(217, 227, 231, 0.9);
  border-radius: 6px;
  background: rgba(243, 247, 247, 0.72);
}

.scientific-question span,
.topic-trajectory span {
  display: block;
  color: var(--teal);
  font-size: 11px;
  font-weight: 800;
  letter-spacing: 0.1em;
  text-transform: uppercase;
}

.scientific-question p {
  margin: 10px 0 0;
  color: var(--ink);
  font-family: var(--serif);
  font-size: clamp(20px, 1.8vw, 28px);
  font-weight: 700;
  line-height: 1.22;
}

.integrated-topic-media {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 10px;
  margin: 28px 0;
}

.research-gallery figure {
  position: relative;
  overflow: hidden;
  min-height: clamp(170px, 15vw, 260px);
  margin: 0;
  border-radius: 6px;
  background: var(--ink);
}

.research-gallery.fna-gallery figure:first-child {
  grid-column: 1 / -1;
  min-height: clamp(230px, 21vw, 340px);
}

.research-gallery img {
  width: 100%;
  height: 100%;
  object-fit: cover;
  filter: saturate(0.94) contrast(1.04);
}

.research-gallery figcaption {
  position: absolute;
  right: 10px;
  bottom: 10px;
  left: 10px;
  padding: 8px 10px;
  border: 1px solid rgba(255, 255, 255, 0.18);
  border-radius: 4px;
  background: rgba(20, 33, 43, 0.72);
  color: var(--white);
  font-size: 12px;
  font-weight: 800;
  line-height: 1.25;
  backdrop-filter: blur(10px);
}

.confluence-canvas {
  position: absolute;
  inset: clamp(12px, 2vw, 34px) clamp(6px, 2vw, 32px) 0;
  z-index: 0;
  width: calc(100% - clamp(12px, 4vw, 64px));
  height: calc(100% - clamp(12px, 2vw, 34px));
  pointer-events: none;
}

.canvas-stream {
  mix-blend-mode: multiply;
}

.canvas-stream-left {
  fill: url("#canvasFna");
}

.canvas-stream-right {
  fill: url("#canvasSurgery");
}

.canvas-stream-merge {
  fill: url("#canvasMerge");
}

.canvas-ridge {
  fill: none;
  stroke: rgba(255, 255, 255, 0.48);
  stroke-linecap: round;
  stroke-width: 2;
}

.flow-source {
  display: grid;
  gap: 10px;
  justify-items: center;
  padding: clamp(22px, 3vw, 34px);
  text-align: center;
}

.flow-source span,
.flow-topic span {
  color: var(--teal);
  font-size: 12px;
  font-weight: 800;
  letter-spacing: 0.1em;
  text-transform: uppercase;
}

.flow-source strong {
  max-width: 760px;
  font-family: var(--serif);
  font-size: clamp(26px, 3vw, 42px);
  line-height: 1.08;
}

.flow-source.clinical {
  border-bottom: 1px solid var(--line);
}

.flow-source.convergence {
  border-top: 1px solid var(--line);
  background: #14212b;
  color: var(--white);
}

.flow-source.convergence span {
  color: #8ccbd0;
}

.flow-source.convergence p {
  max-width: 760px;
  margin: 0;
  color: #c9d3d7;
  font-size: 15px;
  line-height: 1.7;
}

.flow-streams {
  display: grid;
  grid-template-columns: minmax(260px, 1fr) minmax(280px, 0.7fr) minmax(260px, 1fr);
  gap: clamp(18px, 3vw, 34px);
  align-items: stretch;
  padding: clamp(26px, 4vw, 52px);
}

.flow-topic {
  display: flex;
  min-height: 420px;
  flex-direction: column;
  justify-content: flex-end;
  padding: clamp(24px, 3vw, 34px);
  border: 1px solid rgba(20, 33, 43, 0.12);
  border-radius: 8px;
  background: rgba(255, 255, 255, 0.86);
}

.flow-topic.fna {
  box-shadow: inset 5px 0 0 rgba(11, 108, 117, 0.72);
}

.flow-topic.surgery {
  box-shadow: inset 5px 0 0 rgba(31, 95, 154, 0.72);
}

.flow-topic h3 {
  margin: 18px 0 0;
  font-family: var(--serif);
  font-size: clamp(28px, 3vw, 44px);
  line-height: 1.08;
  letter-spacing: 0;
}

.flow-topic p {
  margin: 20px 0 0;
  color: var(--muted);
  font-size: 15px;
  line-height: 1.72;
}

.flow-streams svg {
  align-self: center;
  width: 100%;
  min-height: 480px;
}

.flow-line {
  fill: none;
  stroke-linecap: round;
  stroke-linejoin: round;
}

.flow-line-fna {
  stroke: rgba(11, 108, 117, 0.72);
  stroke-width: 34;
}

.flow-line-surgery {
  stroke: rgba(31, 95, 154, 0.72);
  stroke-width: 34;
}

.flow-line-main {
  stroke: rgba(52, 70, 83, 0.7);
  stroke-width: 24;
}

.flow-node {
  fill: var(--white);
  stroke-width: 8;
}

.flow-node.top-left {
  stroke: var(--teal);
}

.flow-node.top-right {
  stroke: var(--blue);
}

.flow-node.merge {
  stroke: #344653;
}

.research-topic-section {
  display: grid;
  grid-template-columns: minmax(0, 0.98fr) minmax(320px, 0.72fr);
  gap: clamp(32px, 6vw, 94px);
  align-items: center;
  padding: clamp(64px, 8vw, 118px) clamp(20px, 5vw, 76px);
  border-bottom: 1px solid var(--line);
}

.research-topic-section.surgery-topic {
  background: #f3f7f7;
}

.research-topic-copy p {
  margin-top: 24px;
  max-width: 820px;
}

.topic-points {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 1px;
  margin-top: clamp(28px, 4vw, 48px);
  border: 1px solid var(--line);
  background: var(--line);
}

.topic-points.compact {
  grid-template-columns: 1fr;
  margin-top: 28px;
}

.topic-points article {
  min-height: 210px;
  padding: clamp(20px, 2.5vw, 28px);
  background: var(--white);
}

.topic-points.compact article {
  display: grid;
  gap: 18px;
  min-height: 0;
}

.research-topic-section.surgery-topic .topic-points article {
  background: rgba(255, 255, 255, 0.82);
}

.topic-points h3 {
  margin: 0;
  font-family: var(--serif);
  font-size: clamp(21px, 1.9vw, 29px);
  line-height: 1.12;
  letter-spacing: 0;
}

.topic-points h4 {
  margin: 0;
  font-family: var(--serif);
  font-size: clamp(20px, 1.7vw, 26px);
  line-height: 1.14;
  letter-spacing: 0;
}

.topic-points p {
  margin-top: 14px;
  font-size: 14px;
  line-height: 1.62;
}

.topic-point-figure {
  position: relative;
  overflow: hidden;
  margin: 0;
  border-radius: 6px;
  background: var(--ink);
  aspect-ratio: 1 / 1;
}

.topic-point-figure::after {
  position: absolute;
  inset: 0;
  content: "";
  background: linear-gradient(180deg, rgba(20, 33, 43, 0) 44%, rgba(20, 33, 43, 0.72) 100%);
}

.topic-point-figure img {
  width: 100%;
  height: 100%;
  object-fit: cover;
}

.topic-point-figure img[src*="cell-fluorescence"] {
  object-position: center;
}

.topic-point-figure img[src*="hierarchical-cellular-assembly"] {
  object-position: center;
}

.topic-point-figure img[src*="identification-of-matrix-bound-vesicle"] {
  object-position: 48% 48%;
}

.topic-point-figure img[src*="optical-tracking-marker"] {
  object-position: 50% 50%;
}

.topic-point-figure img[src*="ar-navigation-application-test"] {
  object-position: 46% 50%;
}

.topic-point-figure img[src*="in-vitro-model-test"] {
  object-position: 35% 48%;
}

.topic-point-figure figcaption {
  position: absolute;
  right: 14px;
  bottom: 12px;
  left: 14px;
  z-index: 1;
  display: flex;
  align-items: flex-end;
  justify-content: space-between;
  gap: 14px;
  color: var(--white);
}

.topic-point-figure span {
  max-width: 46%;
  color: var(--white);
  font-size: 11px;
  font-weight: 800;
  letter-spacing: 0;
  line-height: 1.22;
  text-transform: uppercase;
}

.topic-point-figure strong {
  max-width: 48%;
  text-align: right;
  font-size: 13px;
  font-weight: 800;
  line-height: 1.25;
}

.topic-trajectory {
  margin-top: 28px;
  padding-top: 24px;
  border-top: 1px solid var(--line);
}

.topic-trajectory ol {
  display: grid;
  gap: 10px;
  margin: 16px 0 0;
  padding: 0;
  list-style: none;
  counter-reset: topic-step;
}

.topic-trajectory li {
  position: relative;
  padding-left: 34px;
  color: #344653;
  font-size: 14px;
  font-weight: 760;
  line-height: 1.45;
  counter-increment: topic-step;
}

.topic-trajectory li::before {
  position: absolute;
  top: -1px;
  left: 0;
  display: grid;
  width: 22px;
  height: 22px;
  place-items: center;
  border-radius: 50%;
  background: var(--ink);
  color: var(--white);
  content: counter(topic-step);
  font-size: 11px;
  font-weight: 800;
}

.convergence-goals {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 1px;
  width: min(940px, 100%);
  margin-top: 20px;
  border-top: 1px solid rgba(255, 255, 255, 0.2);
  border-bottom: 1px solid rgba(255, 255, 255, 0.2);
  background: rgba(255, 255, 255, 0.18);
  text-align: center;
}

.convergence-goals span {
  min-height: 76px;
  padding: 18px;
  background: rgba(255, 255, 255, 0.06);
  color: var(--white);
  font-size: 14px;
  font-weight: 800;
  line-height: 1.35;
}

.research-topic-media {
  display: grid;
  grid-template-columns: 1fr;
  gap: 14px;
}

.research-topic-media img {
  width: 100%;
  height: clamp(220px, 24vw, 360px);
  border-radius: 8px;
  object-fit: cover;
  filter: saturate(0.94) contrast(1.04);
}

.research-topic-media img:first-child {
  height: clamp(300px, 36vw, 520px);
}

.section {
  padding: clamp(68px, 9vw, 128px) clamp(20px, 5vw, 76px);
}

.intro {
  background: var(--paper);
}

.intro-grid {
  display: grid;
  grid-template-columns: minmax(0, 0.9fr) minmax(300px, 0.78fr);
  gap: clamp(30px, 7vw, 108px);
  align-items: start;
}

.intro h2,
.section-heading h2,
.convergence h2,
.translation h2,
.team h2,
.publications h2 {
  font-size: clamp(34px, 4.8vw, 66px);
}

.intro p,
.section-heading p,
.translation-copy p {
  margin: 0;
  color: var(--muted);
  font-size: clamp(16px, 1.35vw, 19px);
  line-height: 1.85;
}

.section-heading {
  display: grid;
  grid-template-columns: minmax(0, 1.05fr) minmax(300px, 0.65fr);
  gap: clamp(28px, 6vw, 92px);
  align-items: end;
  margin-bottom: clamp(34px, 5vw, 64px);
}

.research {
  background: #f3f7f7;
}

.platform-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 22px;
}

.platform-card {
  display: flex;
  min-height: 570px;
  flex-direction: column;
  justify-content: flex-end;
  padding: clamp(26px, 4vw, 48px);
  border: 1px solid rgba(20, 33, 43, 0.12);
  border-radius: 8px;
  background:
    linear-gradient(180deg, rgba(255, 255, 255, 0.14), rgba(255, 255, 255, 0.92)),
    var(--white);
}

.platform-card.biomaterials {
  background:
    linear-gradient(180deg, rgba(243, 247, 247, 0.22), rgba(255, 255, 255, 0.96)),
    radial-gradient(circle at 16% 12%, rgba(11, 108, 117, 0.2), transparent 30%),
    var(--white);
}

.platform-card.surgery {
  background:
    linear-gradient(180deg, rgba(243, 247, 247, 0.12), rgba(255, 255, 255, 0.96)),
    radial-gradient(circle at 86% 14%, rgba(31, 95, 154, 0.18), transparent 32%),
    var(--white);
}

.platform-index {
  margin-bottom: auto;
  color: var(--teal);
  font-family: var(--serif);
  font-size: 34px;
  font-weight: 700;
}

.platform-card h3,
.question-grid h3,
.publication-list h3 {
  margin: 0;
  font-family: var(--serif);
  font-size: clamp(27px, 3vw, 42px);
  line-height: 1.12;
}

.platform-card p {
  max-width: 640px;
  margin: 22px 0 0;
  color: var(--muted);
  font-size: 16px;
  line-height: 1.76;
}

.platform-card ul {
  display: grid;
  gap: 12px;
  margin: 28px 0 0;
  padding: 0;
  list-style: none;
}

.platform-card li {
  position: relative;
  padding-left: 20px;
  color: #344653;
  font-size: 14px;
  font-weight: 650;
}

.platform-card li::before {
  position: absolute;
  top: 0.65em;
  left: 0;
  width: 7px;
  height: 7px;
  border-radius: 50%;
  background: var(--teal);
  content: "";
}

.convergence {
  background: var(--ink);
  color: var(--white);
}

.convergence-panel {
  max-width: 1280px;
  margin: 0 auto;
}

.convergence .eyebrow {
  color: #8ccbd0;
}

.question-grid {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 1px;
  margin-top: 54px;
  background: rgba(255, 255, 255, 0.22);
}

.question-grid article {
  min-height: 320px;
  padding: clamp(24px, 3vw, 36px);
  background: var(--ink);
}

.question-grid span {
  display: block;
  margin-bottom: 70px;
  color: #8ccbd0;
  font-weight: 800;
}

.question-grid h3 {
  font-size: clamp(23px, 2vw, 31px);
}

.question-grid p {
  margin: 20px 0 0;
  color: #c9d3d7;
  font-size: 15px;
}

.translation {
  display: grid;
  grid-template-columns: minmax(0, 0.92fr) minmax(320px, 0.54fr);
  gap: clamp(34px, 7vw, 110px);
  align-items: center;
  background: var(--white);
}

.translation-copy {
  max-width: 820px;
}

.translation-copy p {
  margin-top: 26px;
}

.text-link {
  display: inline-flex;
  margin-top: 28px;
  color: var(--teal);
  font-size: 14px;
  font-weight: 800;
  border-bottom: 2px solid currentColor;
}

.translation-aside {
  display: grid;
  border-top: 1px solid var(--line);
}

.translation-aside div {
  padding: 28px 0;
  border-bottom: 1px solid var(--line);
}

.translation-aside span {
  display: block;
  color: var(--muted);
  font-size: 12px;
  font-weight: 800;
  letter-spacing: 0.1em;
  text-transform: uppercase;
}

.translation-aside strong {
  display: block;
  margin-top: 8px;
  font-family: var(--serif);
  font-size: clamp(24px, 3vw, 38px);
  line-height: 1.1;
}

.translation-hero {
  display: grid;
  grid-template-columns: minmax(0, 0.9fr) minmax(360px, 0.68fr);
  gap: clamp(30px, 6vw, 86px);
  align-items: center;
  min-height: calc(100svh - 76px);
  padding: clamp(52px, 7vw, 96px) clamp(20px, 5vw, 76px) clamp(34px, 5vw, 72px);
  background:
    linear-gradient(90deg, rgba(251, 252, 251, 0.82) 0 42%, rgba(251, 252, 251, 0.38) 100%),
    url("assets/optimized/translation/fyton-pattern.webp") center / 1650px repeat;
}

.translation-hero-copy {
  max-width: 740px;
}

.translation-hero h1,
.translation-system h2,
.translation-pathway h2,
.translation-evidence h2,
.translation-leadership h2,
.translation-challenge h2 {
  margin: 0;
  font-family: var(--serif);
  font-weight: 700;
  letter-spacing: 0;
  line-height: 1.03;
}

.translation-hero h1 {
  font-size: clamp(42px, 5.7vw, 76px);
}

.translation-hero p {
  max-width: 680px;
  margin: 28px 0 0;
  color: var(--muted);
  font-size: clamp(17px, 1.45vw, 21px);
  line-height: 1.72;
}

.translation-hero-visual,
.translation-image-card,
.translation-wide-image,
.translation-leadership-image {
  position: relative;
  overflow: hidden;
  margin: 0;
  border-radius: 8px;
  background: var(--soft);
  box-shadow: var(--shadow);
}

.translation-hero-visual {
  justify-self: center;
  width: min(100%, 560px);
  background: #241b18;
}

.translation-hero-visual img {
  width: 100%;
  height: clamp(540px, 74vh, 800px);
  object-fit: contain;
  object-position: center;
}

.translation-hero-visual::after,
.translation-image-card::after,
.translation-wide-image::after,
.translation-leadership-image::after {
  position: absolute;
  inset: 0;
  content: "";
  background: linear-gradient(180deg, rgba(20, 33, 43, 0) 52%, rgba(20, 33, 43, 0.68) 100%);
  pointer-events: none;
}

.translation-hero-visual figcaption,
.translation-image-card figcaption,
.translation-wide-image figcaption {
  position: absolute;
  right: 20px;
  bottom: 18px;
  left: 20px;
  z-index: 2;
  display: flex;
  align-items: flex-end;
  justify-content: space-between;
  gap: 18px;
  color: var(--white);
}

.translation-hero-visual figcaption span,
.translation-image-card figcaption span,
.translation-wide-image figcaption span {
  font-size: 12px;
  font-weight: 800;
  text-transform: uppercase;
}

.translation-hero-visual figcaption strong,
.translation-image-card figcaption strong,
.translation-wide-image figcaption strong {
  max-width: 230px;
  text-align: right;
  font-size: 14px;
  line-height: 1.35;
}

.translation-pattern-band {
  display: grid;
  grid-template-columns: minmax(0, 0.9fr) minmax(320px, 0.72fr);
  gap: clamp(28px, 6vw, 84px);
  align-items: end;
  padding: 0 clamp(20px, 5vw, 76px) clamp(42px, 5vw, 70px);
  background:
    linear-gradient(90deg, rgba(251, 252, 251, 0.82) 0 42%, rgba(251, 252, 251, 0.38) 100%),
    url("assets/optimized/translation/fyton-pattern.webp") center / 1650px repeat;
  color: var(--ink);
}

.translation-pattern-band span {
  display: block;
  margin-bottom: 14px;
  color: var(--teal);
  font-size: 12px;
  font-weight: 800;
  letter-spacing: 0.12em;
  text-transform: uppercase;
}

.translation-pattern-band p {
  margin: 0;
  color: var(--muted);
  font-size: clamp(16px, 1.4vw, 20px);
  line-height: 1.8;
}

.translation-challenge,
.translation-clinical,
.translation-pathway,
.translation-evidence,
.translation-system,
.translation-leadership {
  padding: clamp(58px, 8vw, 112px) clamp(20px, 5vw, 76px);
  border-bottom: 1px solid var(--line);
}

.compact-heading {
  align-items: end;
  margin-bottom: clamp(34px, 5vw, 62px);
}

.translation-challenge h2,
.translation-pathway h2,
.translation-evidence h2,
.translation-system h2,
.translation-leadership h2 {
  max-width: 850px;
  font-size: clamp(34px, 4.2vw, 60px);
}

.translation-challenge .section-heading p,
.translation-pathway .section-heading p,
.translation-clinical-copy p,
.translation-system-copy p,
.translation-evidence-copy p,
.translation-leadership-copy p {
  max-width: 680px;
  margin: 0;
  color: var(--muted);
  font-size: clamp(16px, 1.25vw, 19px);
  line-height: 1.8;
}

.translation-system-copy p,
.translation-clinical-copy p,
.translation-evidence-copy p,
.translation-leadership-copy p {
  margin-top: 24px;
}

.translation-comparison {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 1px;
  border: 1px solid var(--line);
  background: var(--line);
}

.translation-comparison article {
  min-height: 290px;
  padding: clamp(28px, 4vw, 46px);
  background: var(--white);
}

.translation-comparison span,
.translation-timeline span {
  display: block;
  margin-bottom: 58px;
  color: var(--teal);
  font-size: 12px;
  font-weight: 800;
  letter-spacing: 0.12em;
  text-transform: uppercase;
}

.translation-timeline span {
  margin-bottom: 44px;
  color: var(--blue);
  font-family: var(--serif);
  font-size: 26px;
  letter-spacing: 0;
}

.translation-comparison h3,
.translation-timeline h3 {
  margin: 0;
  font-family: var(--serif);
  font-size: clamp(26px, 3vw, 40px);
  line-height: 1.08;
}

.translation-comparison p,
.translation-timeline p {
  margin: 18px 0 0;
  color: var(--muted);
  font-size: 15px;
  line-height: 1.74;
}

.translation-clinical {
  display: grid;
  grid-template-columns: minmax(260px, 0.46fr) minmax(0, 1fr);
  gap: clamp(34px, 6vw, 86px);
  align-items: start;
}

.translation-clinical-copy {
  position: sticky;
  top: 104px;
}

.translation-clinical-grid {
  display: grid;
  grid-template-columns: minmax(0, 1.05fr) minmax(0, 0.95fr);
  gap: 18px;
}

.translation-clinical-grid .translation-image-card img {
  height: 330px;
  object-position: 50% 50%;
}

.translation-clinical-grid .translation-image-card.large {
  grid-row: span 2;
}

.translation-clinical-grid .translation-image-card.large img {
  height: 678px;
  object-position: 50% 50%;
}

.translation-clinical-grid .translation-image-card:nth-child(2) img {
  object-position: 52% 50%;
}

.translation-clinical-grid .translation-image-card:nth-child(3) img {
  object-position: 50% 48%;
}

.translation-system {
  display: grid;
  grid-template-columns: minmax(280px, 0.55fr) minmax(0, 1fr);
  gap: clamp(34px, 6vw, 86px);
  align-items: start;
  background: #f5f8f8;
}

.translation-system-copy {
  position: sticky;
  top: 104px;
}

.translation-system-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 18px;
}

.translation-image-card img {
  width: 100%;
  height: 340px;
  object-fit: cover;
}

.translation-image-card.large {
  grid-row: span 2;
}

.translation-image-card.large img {
  height: 698px;
  object-position: center;
}

.translation-image-card:nth-child(2) img {
  object-position: 50% 54%;
}

.translation-image-card:nth-child(3) img {
  object-position: 52% 44%;
}

.translation-timeline {
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  gap: 1px;
  border: 1px solid var(--line);
  background: var(--line);
}

.translation-timeline article {
  min-height: 330px;
  padding: clamp(26px, 3.5vw, 42px);
  background: var(--white);
}

.translation-evidence {
  display: grid;
  grid-template-columns: minmax(260px, 0.48fr) minmax(0, 1fr);
  gap: clamp(32px, 6vw, 84px);
  align-items: center;
}

.translation-education-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 18px;
}

.translation-education-grid .translation-image-card img {
  height: clamp(390px, 42vw, 560px);
  object-fit: cover;
}

.translation-education-grid .translation-image-card:first-child img {
  object-position: 50% 48%;
}

.translation-education-grid .translation-image-card:nth-child(2) img {
  object-position: 50% 56%;
}

.translation-wide-image img {
  width: 100%;
  height: clamp(420px, 52vw, 620px);
  object-fit: cover;
  object-position: 46% 50%;
}

.translation-leadership {
  display: grid;
  grid-template-columns: minmax(320px, 0.75fr) minmax(0, 0.85fr);
  gap: clamp(32px, 6vw, 88px);
  align-items: center;
  background:
    linear-gradient(90deg, rgba(251, 252, 251, 0.8), rgba(251, 252, 251, 0.5)),
    url("assets/optimized/translation/fyton-pattern.webp") center / 1650px repeat;
}

.translation-leadership-image img {
  width: 100%;
  height: clamp(380px, 42vw, 560px);
  object-fit: cover;
  object-position: 50% 52%;
}

.translation-leadership-copy {
  max-width: 780px;
}

.team {
  background: #eef3f4;
}

.photo-grid {
  display: grid;
  grid-template-columns: 1.2fr 0.8fr 0.8fr;
  grid-auto-rows: minmax(260px, 29vw);
  gap: 16px;
}

.photo-grid img {
  width: 100%;
  height: 100%;
  border-radius: 8px;
  object-fit: cover;
  object-position: center;
}

.photo-grid .wide {
  grid-row: span 2;
}

.people-hero {
  grid-template-columns: minmax(240px, 0.38fr) minmax(0, 0.62fr);
  align-items: center;
  padding-top: clamp(42px, 6vw, 76px);
  padding-bottom: clamp(42px, 6vw, 76px);
}

.people-hero h1 {
  font-size: clamp(46px, 7vw, 82px);
}

.people-hero-copy p:not(.eyebrow) {
  max-width: 460px;
  margin-top: 20px;
  color: var(--muted);
  font-size: clamp(15px, 1.15vw, 18px);
  line-height: 1.72;
}

.people-hero-gallery {
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  grid-template-rows: 1.58fr 0.78fr;
  gap: 12px;
  height: clamp(380px, 34vw, 520px);
}

.people-hero-gallery img {
  width: 100%;
  height: 100%;
  min-width: 0;
  min-height: 0;
  border-radius: 8px;
  filter: brightness(0.94) contrast(1.04) saturate(0.92);
  object-fit: cover;
  object-position: center;
}

.people-hero-gallery .wide {
  grid-column: span 4;
  grid-row: 1;
  filter: brightness(0.88) contrast(1.06) saturate(0.88);
}

.people-hero-gallery img:nth-child(2) {
  object-position: 58% 50%;
}

.people-hero-gallery img:nth-child(3) {
  object-position: 50% 42%;
}

.people-hero-gallery img:nth-child(4) {
  object-position: 50% 58%;
}

.people-hero-gallery img:nth-child(5) {
  object-position: 50% 52%;
}

.people-section {
  padding: clamp(42px, 6vw, 82px) clamp(20px, 5vw, 76px);
  border-bottom: 1px solid var(--line);
  background: var(--paper);
}

.people-section:nth-of-type(odd) {
  background: #f3f7f7;
}

.people-lead {
  position: relative;
  overflow: hidden;
  background: var(--ink);
}

.people-lead::before {
  position: absolute;
  inset: -12% 0;
  z-index: 0;
  background-image:
    linear-gradient(90deg, rgba(20, 33, 43, 0.86) 0%, rgba(20, 33, 43, 0.62) 43%, rgba(20, 33, 43, 0.34) 100%),
    url("assets/team/pi-surgery-bg.jpeg");
  background-position:
    center,
    center 46%;
  background-repeat: no-repeat;
  background-size:
    cover,
    cover;
  content: "";
  filter: contrast(1.08) brightness(0.9);
  transform: translate3d(0, var(--pi-bg-y, 0px), 0);
  animation: piBackgroundDrift 18s ease-in-out infinite alternate;
  will-change: transform;
}

@keyframes piBackgroundDrift {
  from {
    background-position:
      center,
      center 43%;
    filter: contrast(1.08) brightness(0.86);
  }

  to {
    background-position:
      center,
      center 57%;
    filter: contrast(1.12) brightness(0.94);
  }
}

.people-lead .people-section-header,
.people-lead .person-card {
  position: relative;
  z-index: 1;
}

.people-lead .people-section-header h2 {
  color: var(--white);
}

.people-lead .person-card-featured {
  border-color: rgba(255, 255, 255, 0.24);
  background: rgba(255, 255, 255, 0.9);
  box-shadow: 0 24px 70px rgba(0, 0, 0, 0.22);
  backdrop-filter: blur(12px);
}

.people-section-header {
  margin-bottom: clamp(22px, 3vw, 34px);
}

.people-section-header h2 {
  margin: 0;
  font-family: var(--serif);
  font-size: clamp(30px, 3.6vw, 50px);
  line-height: 1.05;
  letter-spacing: 0;
}

.people-grid {
  display: grid;
  grid-template-columns: repeat(auto-fill, minmax(220px, 260px));
  gap: 22px;
  justify-content: start;
}

.people-grid-small {
  grid-template-columns: repeat(auto-fill, minmax(220px, 260px));
}

.person-card {
  overflow: hidden;
  min-width: 0;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: var(--white);
}

.person-card-featured {
  display: grid;
  grid-template-columns: 300px minmax(0, 1fr);
  max-width: 880px;
}

.person-card img {
  width: 100%;
  height: 300px;
  object-fit: cover;
  object-position: center top;
  background: #e7ecee;
}

.person-card-featured img {
  width: 300px;
  height: 100%;
  min-height: 360px;
}

.person-body {
  padding: 18px;
}

.person-card-featured .person-body {
  display: flex;
  flex-direction: column;
  justify-content: flex-end;
  padding: clamp(24px, 4vw, 44px);
}

.person-card h3 {
  margin: 0;
  font-family: var(--serif);
  font-size: clamp(23px, 2vw, 30px);
  line-height: 1.12;
  letter-spacing: 0;
}

.person-card-featured h3 {
  font-size: clamp(34px, 4vw, 54px);
}

.cn-name {
  margin: 6px 0 0;
  color: var(--muted);
  font-size: 14px;
  font-weight: 700;
}

.person-description {
  margin: 16px 0 0;
  color: var(--muted);
  font-size: 14px;
  line-height: 1.58;
}

.person-description span {
  display: block;
  margin-top: 5px;
}

.person-description span:first-child {
  margin-top: 0;
  color: #344653;
  font-weight: 700;
}

.person-description-spaced {
  margin-top: 22px;
  font-size: 15px;
  line-height: 1.68;
}

.person-description-spaced span {
  margin-top: 8px;
}

.publications {
  background: var(--paper);
}

.publication-metrics {
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  border-bottom: 1px solid var(--line);
  background: var(--white);
}

.publication-metrics div {
  min-height: 150px;
  padding: 28px clamp(20px, 4vw, 44px);
  border-right: 1px solid var(--line);
}

.publication-metrics div:last-child {
  border-right: 0;
}

.publication-metrics strong {
  display: block;
  color: var(--blue);
  font-family: var(--serif);
  font-size: clamp(34px, 3.6vw, 52px);
  line-height: 1;
}

.publication-metrics span {
  display: block;
  max-width: 260px;
  margin-top: 14px;
  color: var(--muted);
  font-size: 14px;
  line-height: 1.5;
}

.publication-visual-section {
  padding: clamp(48px, 6vw, 84px) clamp(20px, 5vw, 76px);
  border-bottom: 1px solid var(--line);
  background: var(--white);
}

.trajectory-section {
  background: var(--paper);
}

.publication-visual-header {
  margin-bottom: clamp(24px, 4vw, 42px);
}

.publication-visual-header h2 {
  max-width: 980px;
  margin: 0;
  font-family: var(--serif);
  font-size: clamp(32px, 4.4vw, 64px);
  line-height: 1.05;
  letter-spacing: 0;
}

.output-map {
  display: grid;
  gap: 1px;
  border: 1px solid var(--line);
  background: var(--line);
}

.output-theme {
  display: grid;
  grid-template-columns: minmax(0, 0.72fr) minmax(320px, 0.48fr);
  gap: clamp(22px, 4vw, 54px);
  align-items: center;
  padding: clamp(22px, 3vw, 34px);
  background: var(--white);
}

.output-theme h3 {
  margin: 0;
  font-family: var(--serif);
  font-size: clamp(24px, 2.6vw, 38px);
  line-height: 1.08;
  letter-spacing: 0;
}

.output-theme p {
  max-width: 660px;
  margin: 12px 0 0;
  color: var(--muted);
  font-size: 14px;
  line-height: 1.62;
}

.output-bars {
  display: grid;
  gap: 10px;
}

.output-bars span {
  position: relative;
  display: flex;
  align-items: center;
  justify-content: space-between;
  overflow: hidden;
  min-height: 42px;
  padding: 0 14px;
  border-radius: 4px;
  color: var(--ink);
  font-size: 13px;
  font-weight: 800;
}

.output-bars span::before {
  position: absolute;
  inset: 0 auto 0 0;
  z-index: 0;
  width: calc(var(--value) / 17 * 100%);
  min-width: 34px;
  content: "";
  opacity: 0.28;
}

.output-bars span strong {
  position: relative;
  z-index: 1;
  font-family: var(--serif);
  font-size: 27px;
  line-height: 1;
}

.output-bars span:not(strong) {
  position: relative;
}

.paper-bar {
  border: 1px solid rgba(11, 108, 117, 0.2);
  background: rgba(11, 108, 117, 0.05);
  --value: var(--papers);
}

.paper-bar::before {
  background: var(--teal);
}

.patent-bar {
  border: 1px solid rgba(31, 95, 154, 0.2);
  background: rgba(31, 95, 154, 0.05);
  --value: var(--patents);
}

.patent-bar::before {
  background: var(--blue);
}

.timeline-panel {
  overflow: hidden;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: var(--white);
}

.timeline-legend {
  display: flex;
  gap: 22px;
  padding: 22px clamp(20px, 4vw, 34px);
  border-bottom: 1px solid var(--line);
}

.timeline-legend span {
  display: inline-flex;
  align-items: center;
  gap: 8px;
  color: var(--muted);
  font-size: 13px;
  font-weight: 800;
}

.timeline-legend i {
  display: inline-block;
  width: 26px;
  height: 8px;
  border-radius: 99px;
}

.legend-paper {
  background: var(--teal);
}

.legend-patent {
  background: var(--blue);
}

.timeline-bars {
  display: grid;
  grid-template-columns: repeat(11, minmax(70px, 1fr));
  gap: 1px;
  align-items: end;
  min-height: 300px;
  background: var(--line);
}

.timeline-year {
  display: grid;
  align-items: end;
  min-height: 300px;
  padding: 18px 10px 16px;
  background: #fbfcfb;
}

.bar-pair {
  display: flex;
  align-items: flex-end;
  justify-content: center;
  gap: 8px;
  height: 190px;
  border-bottom: 1px solid rgba(20, 33, 43, 0.22);
}

.paper-bar-vertical,
.patent-bar-vertical {
  display: flex;
  align-items: flex-start;
  justify-content: center;
  width: 24px;
  min-height: 6px;
  border-radius: 4px 4px 0 0;
  color: var(--white);
  font-size: 10px;
  font-weight: 800;
}

.paper-bar-vertical {
  height: calc(var(--papers) * 12px);
  background: var(--teal);
}

.patent-bar-vertical {
  height: calc(var(--patents) * 12px);
  background: var(--blue);
}

.paper-bar-vertical b,
.patent-bar-vertical b {
  display: block;
  margin-top: 5px;
  line-height: 1;
}

.timeline-year strong {
  display: block;
  margin-top: 14px;
  color: var(--muted);
  font-size: 12px;
  text-align: center;
}

.research-river-panel {
  position: relative;
  overflow: hidden;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: linear-gradient(180deg, #ffffff 0%, #f7faf9 100%);
}

.research-river-summary {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  border-bottom: 1px solid var(--line);
}

.research-river-summary div {
  padding: clamp(20px, 3vw, 32px);
  border-right: 1px solid var(--line);
}

.research-river-summary div:last-child {
  border-right: 0;
}

.research-river-summary strong {
  display: block;
  color: var(--blue);
  font-family: var(--serif);
  font-size: clamp(34px, 4vw, 56px);
  line-height: 1;
}

.research-river-summary span {
  display: block;
  margin-top: 8px;
  color: var(--muted);
  font-size: 13px;
  font-weight: 800;
  line-height: 1.35;
  text-transform: uppercase;
}

.research-river-guide {
  display: flex;
  flex-wrap: wrap;
  gap: 12px 22px;
  align-items: center;
  padding: 18px clamp(20px, 4vw, 34px);
  border-bottom: 1px solid var(--line);
  color: #344653;
  font-size: 13px;
  font-weight: 800;
}

.research-river-guide span {
  display: inline-flex;
  align-items: center;
  gap: 9px;
}

.guide-line {
  display: inline-block;
  width: 34px;
  height: 6px;
  border-radius: 99px;
  background: var(--teal);
}

.research-river-canvas {
  overflow-x: auto;
  padding: clamp(16px, 2vw, 24px);
}

.research-river-canvas svg {
  display: block;
  width: 100%;
  min-width: 980px;
  min-height: 420px;
}

.river-grid line {
  stroke: rgba(217, 227, 231, 0.62);
  stroke-width: 1;
}

.river-output-axis line {
  stroke: rgba(52, 70, 83, 0.24);
  stroke-width: 1.2;
}

.river-output-axis text {
  fill: var(--muted);
  font-size: 14px;
  font-weight: 800;
  text-anchor: end;
}

.river-output-axis .axis-title {
  fill: #344653;
  font-size: 15px;
  text-anchor: start;
}

.river-output-bars rect {
  fill: rgba(31, 95, 154, 0.075);
  stroke: rgba(31, 95, 154, 0.13);
  stroke-width: 1;
}

.river-paths .river {
  opacity: 0.74;
}

.river-publications circle {
  stroke: var(--white);
  stroke-width: 5;
  filter: drop-shadow(0 8px 10px rgba(20, 33, 43, 0.12));
}

.river-patents rect {
  rx: 3px;
  stroke: var(--white);
  stroke-width: 3;
  filter: drop-shadow(0 6px 8px rgba(20, 33, 43, 0.12));
}

.river-node {
  cursor: pointer;
  outline: none;
  transition: opacity 180ms ease, transform 180ms ease;
}

.river-node:hover,
.river-node:focus {
  opacity: 1;
}

.river-node:focus {
  stroke: #111a21;
  stroke-width: 5;
}

.patent-delivery {
  fill: var(--teal);
}

.patent-regeneration {
  fill: var(--green);
}

.patent-immune {
  fill: #b58a33;
}

.patent-surgery {
  fill: var(--blue);
}

.river-years text {
  fill: var(--muted);
  font-size: 15px;
  font-weight: 800;
  text-anchor: middle;
}

.research-river-stats {
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  gap: 1px;
  background: var(--line);
  border-top: 1px solid var(--line);
}

.research-river-stats article {
  display: flex;
  flex-direction: column;
  min-height: 150px;
  padding: 22px;
  background: rgba(255, 255, 255, 0.88);
}

.research-river-stats i {
  display: block;
  width: 36px;
  height: 5px;
  margin-bottom: 16px;
  border-radius: 99px;
}

.research-river-stats h3 {
  margin: 0;
  font-family: var(--serif);
  font-size: clamp(20px, 1.8vw, 28px);
  line-height: 1.08;
  letter-spacing: 0;
}

.research-river-stats p {
  margin: auto 0 0;
  padding-top: 22px;
  color: var(--muted);
  font-size: 13px;
  font-weight: 760;
  line-height: 1.6;
}

.research-river-stats p strong {
  color: var(--ink);
  font-family: var(--serif);
  font-size: 22px;
  line-height: 1;
}

.research-river-legend {
  display: flex;
  flex-wrap: wrap;
  gap: 12px 22px;
  align-items: center;
  padding: 18px clamp(20px, 4vw, 34px) 22px;
  border-top: 1px solid var(--line);
  color: var(--muted);
  font-size: 13px;
  font-weight: 800;
}

.research-river-legend span {
  display: inline-flex;
  align-items: center;
  gap: 8px;
}

.legend-paper-dot,
.legend-patent-square {
  display: inline-block;
  width: 12px;
  height: 12px;
  background: var(--teal);
}

.legend-paper-dot {
  border-radius: 50%;
}

.legend-patent-square {
  border-radius: 3px;
  background: var(--blue);
}

.river-tooltip {
  position: absolute;
  z-index: 5;
  max-width: min(460px, calc(100% - 28px));
  padding: 14px 16px;
  border: 1px solid rgba(20, 33, 43, 0.16);
  border-radius: 6px;
  background: rgba(255, 255, 255, 0.96);
  box-shadow: 0 18px 44px rgba(20, 33, 43, 0.18);
  color: var(--ink);
  font-size: 13px;
  font-weight: 760;
  line-height: 1.55;
  opacity: 0;
  pointer-events: none;
  transform: translate(-50%, -100%);
  transition: opacity 140ms ease;
}

.river-tooltip.visible {
  opacity: 1;
}

.sankey-panel {
  position: relative;
  overflow: hidden;
  min-height: 430px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: linear-gradient(180deg, #ffffff 0%, #f6f9f9 100%);
}

.sankey-flows {
  position: absolute;
  inset: 0;
  width: 100%;
  height: 100%;
  pointer-events: none;
}

.flow {
  fill: none;
  stroke-linecap: round;
  opacity: 0.34;
}

.flow-teal {
  stroke: var(--teal);
  stroke-width: 34;
}

.flow-green {
  stroke: var(--green);
  stroke-width: 30;
}

.flow-blue {
  stroke: var(--blue);
  stroke-width: 26;
}

.flow-gold {
  stroke: #b58a33;
  stroke-width: 22;
}

.flow-ink {
  stroke: #344653;
  stroke-width: 18;
}

.sankey-columns {
  position: relative;
  z-index: 1;
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: clamp(22px, 4vw, 60px);
  min-height: 430px;
  padding: clamp(24px, 4vw, 48px);
}

.sankey-column {
  display: grid;
  align-content: start;
  gap: 16px;
}

.sankey-column h3 {
  margin: 0 0 8px;
  color: #344653;
  font-size: 12px;
  font-weight: 800;
  letter-spacing: 0.1em;
  text-transform: uppercase;
}

.sankey-node {
  display: block;
  min-height: 54px;
  padding: 14px 16px;
  border: 1px solid rgba(217, 227, 231, 0.9);
  border-radius: 8px;
  background: rgba(255, 255, 255, 0.88);
  color: var(--ink);
  font-size: 14px;
  font-weight: 760;
  line-height: 1.35;
  box-shadow: 0 12px 32px rgba(20, 33, 43, 0.08);
  backdrop-filter: blur(10px);
}

.node-teal {
  border-left: 5px solid var(--teal);
}

.node-green {
  border-left: 5px solid var(--green);
}

.node-gold {
  border-left: 5px solid #b58a33;
}

.node-blue {
  border-left: 5px solid var(--blue);
}

.trajectory-panel {
  overflow: hidden;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: var(--white);
}

.trajectory-panel svg {
  display: block;
  width: 100%;
  min-height: 360px;
}

.trajectory-grid line {
  stroke: rgba(217, 227, 231, 0.9);
  stroke-width: 1;
}

.river {
  fill: none;
  stroke-linecap: round;
  stroke-linejoin: round;
  opacity: 0.78;
}

.river-foundation {
  stroke: #344653;
  stroke-width: 28;
}

.river-delivery {
  stroke: var(--teal);
  stroke-width: 34;
}

.river-regeneration {
  stroke: var(--green);
  stroke-width: 30;
}

.river-immune {
  stroke: #b58a33;
  stroke-width: 24;
}

.river-surgery {
  stroke: var(--blue);
  stroke-width: 22;
}

.trajectory-labels text {
  fill: var(--muted);
  font-size: 18px;
  font-weight: 700;
  text-anchor: middle;
}

.trajectory-points circle {
  stroke: var(--white);
  stroke-width: 4;
}

.point-foundation {
  fill: #344653;
}

.point-delivery {
  fill: var(--teal);
}

.point-regeneration {
  fill: var(--green);
}

.point-immune {
  fill: #b58a33;
}

.point-surgery {
  fill: var(--blue);
}

.trajectory-legend {
  display: flex;
  flex-wrap: wrap;
  gap: 12px 22px;
  padding: 22px clamp(20px, 4vw, 34px) 26px;
  border-top: 1px solid var(--line);
}

.trajectory-legend span {
  display: inline-flex;
  align-items: center;
  gap: 8px;
  color: var(--muted);
  font-size: 13px;
  font-weight: 700;
}

.trajectory-legend i {
  display: inline-block;
  width: 24px;
  height: 5px;
  border-radius: 99px;
}

.legend-foundation {
  background: #344653;
}

.legend-delivery {
  background: var(--teal);
}

.legend-regeneration {
  background: var(--green);
}

.legend-immune {
  background: #b58a33;
}

.legend-surgery {
  background: var(--blue);
}

.patent-section {
  background: #f3f7f7;
}

.patent-overview {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 1px;
  margin-bottom: clamp(24px, 4vw, 42px);
  border: 1px solid var(--line);
  background: var(--line);
}

.patent-overview article {
  min-height: 150px;
  padding: clamp(22px, 3vw, 34px);
  background: var(--white);
}

.patent-overview strong {
  display: block;
  font-family: var(--serif);
  font-size: clamp(24px, 2.5vw, 36px);
  line-height: 1.1;
  letter-spacing: 0;
}

.patent-overview span {
  display: block;
  max-width: 520px;
  margin-top: 16px;
  color: var(--muted);
  font-size: 14px;
  line-height: 1.62;
}

.patent-grid {
  display: grid;
  grid-template-columns: minmax(0, 0.95fr) minmax(0, 1.25fr);
  gap: clamp(20px, 4vw, 42px);
}

.patent-track {
  min-width: 0;
  border-top: 1px solid var(--line);
}

.patent-track h3 {
  margin: 0;
  padding: 22px 0;
  color: #344653;
  font-size: 12px;
  font-weight: 800;
  letter-spacing: 0.1em;
  text-transform: uppercase;
}

.patent-item {
  display: grid;
  gap: 8px;
  padding: 18px 0;
  border-top: 1px solid var(--line);
}

.patent-item span {
  color: var(--teal);
  font-size: 12px;
  font-weight: 800;
  letter-spacing: 0.06em;
  text-transform: uppercase;
}

.patent-item h4 {
  margin: 0;
  font-family: var(--serif);
  font-size: clamp(19px, 1.6vw, 25px);
  line-height: 1.2;
  letter-spacing: 0;
}

.patent-item p {
  margin: 0;
  color: var(--muted);
  font-size: 13px;
  line-height: 1.5;
}

.publication-section {
  padding: clamp(52px, 7vw, 96px) clamp(20px, 5vw, 76px);
  border-bottom: 1px solid var(--line);
  background: var(--paper);
}

.publication-list-section {
  background: #f3f7f7;
}

.publication-section-header {
  display: flex;
  align-items: flex-end;
  justify-content: space-between;
  gap: 22px;
  margin-bottom: clamp(28px, 4vw, 46px);
}

.publication-section-header h2 {
  margin: 0;
  font-family: var(--serif);
  font-size: clamp(32px, 4vw, 58px);
  line-height: 1.05;
  letter-spacing: 0;
}

.publication-section-header a,
.publication-section-header span {
  color: var(--teal);
  font-size: 13px;
  font-weight: 800;
  letter-spacing: 0.06em;
  text-transform: uppercase;
}

.publication-section-header a {
  border-bottom: 2px solid currentColor;
}

.featured-publication-grid {
  display: grid;
  grid-template-columns: repeat(5, minmax(0, 1fr));
  gap: 1px;
  border: 1px solid var(--line);
  background: var(--line);
}

.featured-publication {
  display: flex;
  min-height: 420px;
  flex-direction: column;
  padding: 22px;
  background: var(--white);
}

.featured-publication span {
  color: var(--teal);
  font-size: 12px;
  font-weight: 800;
  letter-spacing: 0.06em;
  text-transform: uppercase;
}

.featured-publication h3 {
  margin: 30px 0 0;
  font-family: var(--serif);
  font-size: clamp(20px, 1.6vw, 26px);
  line-height: 1.16;
  letter-spacing: 0;
}

.featured-publication p {
  margin: 18px 0 0;
  color: var(--muted);
  font-size: 14px;
  line-height: 1.62;
}

.featured-publication-meta {
  display: grid;
  gap: 14px;
  margin-top: auto;
  padding-top: 24px;
}

.featured-publication .featured-citations {
  display: block;
  color: #344653;
  font-size: 12px;
  font-weight: 800;
  letter-spacing: 0;
  text-transform: none;
}

.featured-publication strong {
  display: block;
  color: #344653;
  font-size: 13px;
}

.featured-publication a,
.publication-links a {
  display: inline-flex;
  color: var(--teal);
  font-size: 13px;
  font-weight: 800;
  border-bottom: 2px solid currentColor;
}

.featured-publication a {
  align-self: flex-start;
}

.publication-list-full {
  padding: 0 clamp(18px, 3vw, 34px);
  border-top: 1px solid var(--line);
  border-right: 1px solid var(--line);
  border-left: 1px solid var(--line);
  background: var(--white);
}

.publication-item {
  display: grid;
  grid-template-columns: 86px minmax(0, 1fr) minmax(120px, auto);
  gap: clamp(18px, 2.4vw, 34px);
  padding: 24px 0;
  border-bottom: 1px solid var(--line);
}

.publication-year {
  color: var(--blue);
  font-family: var(--serif);
  font-size: 24px;
  font-weight: 700;
  line-height: 1.1;
}

.publication-main {
  min-width: 0;
}

.publication-main h3 {
  margin: 0;
  font-family: var(--serif);
  font-size: clamp(20px, 2vw, 28px);
  line-height: 1.18;
  letter-spacing: 0;
}

.publication-authors,
.publication-journal {
  margin: 10px 0 0;
  color: var(--muted);
  font-size: 14px;
  line-height: 1.55;
}

.publication-authors strong {
  color: var(--ink);
}

.publication-journal {
  color: #344653;
  font-weight: 700;
}

.publication-links {
  display: flex;
  align-items: flex-start;
  flex-direction: column;
  gap: 8px;
  justify-content: flex-end;
  padding-top: 4px;
  white-space: nowrap;
}

.citation-count {
  color: var(--muted);
  font-size: 12px;
  font-weight: 800;
}

.publication-list {
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  gap: 1px;
  background: var(--line);
  border: 1px solid var(--line);
}

.publication-list article {
  min-height: 300px;
  padding: 28px;
  background: var(--white);
}

.publication-list span {
  display: block;
  margin-bottom: 44px;
  color: var(--teal);
  font-size: 12px;
  font-weight: 800;
  letter-spacing: 0.06em;
  text-transform: uppercase;
}

.publication-list h3 {
  font-size: clamp(21px, 1.8vw, 28px);
}

.site-footer {
  display: grid;
  grid-template-columns: minmax(0, 0.9fr) minmax(280px, 0.55fr);
  gap: 30px;
  padding: 54px clamp(20px, 5vw, 76px);
  background: var(--ink);
  color: var(--white);
}

.site-footer h2 {
  font-size: clamp(32px, 4vw, 54px);
}

.site-footer p {
  max-width: 620px;
  margin: 12px 0 0;
  color: #c9d3d7;
}

.footer-links {
  display: grid;
  gap: 10px;
  align-content: start;
  justify-items: end;
}

.footer-links a {
  color: #dfe8eb;
  font-size: 14px;
  font-weight: 700;
}

.footer-links a:hover {
  color: #8ccbd0;
}

@media (max-width: 1040px) {
  .site-header {
    position: static;
    align-items: flex-start;
    flex-direction: column;
  }

  .site-nav {
    justify-content: flex-start;
  }

  .people-hero,
  .hero,
  .intro-grid,
  .section-heading,
  .research-flow-header,
  .research-topic-section,
  .translation,
  .translation-hero,
  .translation-pattern-band,
  .translation-clinical,
  .translation-system,
  .translation-evidence,
  .translation-leadership,
  .site-footer {
    grid-template-columns: 1fr;
  }

  .hero {
    min-height: auto;
  }

  .hero-visual {
    min-height: 0;
  }

  .metrics,
  .publication-metrics,
  .home-summary,
  .platform-grid,
  .question-grid,
  .publication-list,
  .page-link-grid,
  .clinical-question-row,
  .convergence-goals {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .people-grid-small {
    grid-template-columns: repeat(auto-fill, minmax(220px, 260px));
  }

  .featured-publication-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .research-river-stats {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .translation-system-copy,
  .translation-clinical-copy {
    position: static;
  }

  .translation-hero-visual img,
  .translation-image-card.large img,
  .translation-clinical-grid .translation-image-card.large img {
    height: 560px;
  }

  .translation-timeline {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .flow-streams,
  .integrated-flow-grid {
    grid-template-columns: 1fr;
  }

  .flow-topic.fna,
  .integrated-topic.fna {
    order: 1;
  }

  .flow-topic.surgery,
  .integrated-topic.surgery {
    order: 2;
  }

  .confluence-canvas {
    display: none;
  }

  .topic-points {
    grid-template-columns: 1fr;
  }

  .people-hero-gallery {
    grid-template-rows: minmax(220px, 28vw) minmax(110px, 14vw);
    height: clamp(360px, 42vw, 500px);
  }

  .footer-links {
    justify-items: start;
  }
}

@media (max-width: 720px) {
  .site-header {
    gap: 14px;
    min-height: 0;
    padding: 14px 18px;
  }

  .brand {
    min-width: 0;
  }

  .site-nav {
    gap: 4px 15px;
    font-size: 13px;
  }

  .hero {
    padding: 38px 18px 24px;
  }

  .hero h1 {
    font-size: clamp(38px, 11vw, 49px);
  }

  .hero-actions {
    flex-direction: column;
  }

  .button {
    width: 100%;
  }

  .hero-visual img {
    height: 430px;
  }

  .hero-caption {
    align-items: flex-start;
    flex-direction: column;
  }

  .hero-caption strong {
    text-align: left;
  }

  .metrics,
  .publication-metrics,
  .home-summary,
  .platform-grid,
  .question-grid,
  .publication-list,
  .page-link-grid,
  .clinical-question-row,
  .convergence-goals,
  .translation-comparison,
  .translation-clinical-grid,
  .translation-system-grid,
  .translation-education-grid,
  .translation-timeline,
  .page-hero {
    grid-template-columns: 1fr;
  }

  .metrics div {
    min-height: 0;
    border-right: 0;
    border-bottom: 1px solid var(--line);
  }

  .publication-metrics div {
    min-height: 0;
    border-right: 0;
    border-bottom: 1px solid var(--line);
  }

  .metrics div:last-child {
    border-bottom: 0;
  }

  .publication-metrics div:last-child {
    border-bottom: 0;
  }

  .home-summary article,
  .page-link-grid article {
    min-height: 0;
  }

  .home-summary span,
  .page-link-grid span {
    margin-bottom: 38px;
  }

  .home-photo-band {
    grid-template-columns: 1fr;
  }

  .home-photo-band img {
    height: 280px;
  }

  .translation-hero {
    padding: 42px 18px 30px;
  }

  .translation-hero h1 {
    font-size: clamp(38px, 11vw, 50px);
  }

  .translation-hero-visual img {
    height: 430px;
  }

  .translation-hero-visual figcaption,
  .translation-image-card figcaption,
  .translation-wide-image figcaption {
    align-items: flex-start;
    flex-direction: column;
  }

  .translation-hero-visual figcaption strong,
  .translation-image-card figcaption strong,
  .translation-wide-image figcaption strong {
    text-align: left;
  }

  .translation-pattern-band,
  .translation-challenge,
  .translation-clinical,
  .translation-pathway,
  .translation-evidence,
  .translation-system,
  .translation-leadership {
    padding: 54px 18px;
  }

  .translation-pattern-band {
    padding-top: 0;
  }

  .translation-comparison article,
  .translation-timeline article {
    min-height: 0;
  }

  .translation-comparison span,
  .translation-timeline span {
    margin-bottom: 32px;
  }

  .translation-image-card img,
  .translation-image-card.large img,
  .translation-clinical-grid .translation-image-card.large img,
  .translation-wide-image img,
  .translation-leadership-image img {
    height: 330px;
  }

  .page-hero {
    padding: 58px 18px;
  }

  .clinical-challenge-hero {
    padding: 64px 18px;
  }

  .clinical-question-row span {
    min-height: 0;
  }

  .research-flow-section,
  .research-topic-section {
    padding-right: 18px;
    padding-left: 18px;
  }

  .flow-streams,
  .integrated-flow-grid {
    padding: 18px;
  }

  .flow-topic,
  .integrated-topic {
    min-height: 300px;
  }

  .integrated-topic-media {
    grid-template-columns: 1fr;
  }

  .topic-point-figure figcaption {
    align-items: flex-start;
    flex-direction: column;
    gap: 5px;
  }

  .topic-point-figure span,
  .topic-point-figure strong {
    max-width: 100%;
    text-align: left;
  }

  .people-hero {
    padding-top: 42px;
    padding-bottom: 42px;
  }

  .people-hero-gallery {
    grid-template-columns: repeat(2, minmax(0, 1fr));
    grid-template-rows: 170px 118px 118px;
    gap: 10px;
    height: auto;
  }

  .people-hero-gallery .wide {
    grid-column: span 2;
    grid-row: span 1;
  }

  .section {
    padding: 64px 18px;
  }

  .publication-section {
    padding: 52px 18px;
  }

  .publication-visual-section {
    padding: 48px 18px;
  }

  .sankey-panel {
    min-height: 0;
  }

  .output-theme {
    grid-template-columns: 1fr;
  }

  .timeline-panel {
    overflow-x: auto;
  }

  .timeline-bars {
    width: 920px;
  }

  .research-river-summary,
  .research-river-stats {
    grid-template-columns: 1fr;
  }

  .research-river-summary div {
    border-right: 0;
    border-bottom: 1px solid var(--line);
  }

  .research-river-summary div:last-child {
    border-bottom: 0;
  }

  .research-river-canvas {
    padding: 12px;
  }

  .research-river-canvas svg {
    width: 980px;
    min-height: 430px;
  }

  .research-river-stats article {
    min-height: 0;
    padding: 20px;
  }

  .sankey-flows {
    opacity: 0.28;
  }

  .sankey-columns {
    grid-template-columns: 1fr;
    min-height: 0;
    padding: 22px;
  }

  .sankey-node {
    min-height: 0;
  }

  .patent-overview,
  .patent-grid {
    grid-template-columns: 1fr;
  }

  .trajectory-panel {
    overflow-x: auto;
  }

  .trajectory-panel svg {
    width: 920px;
    min-height: 340px;
  }

  .publication-section-header {
    align-items: flex-start;
    flex-direction: column;
  }

  .featured-publication {
    min-height: 0;
  }

  .featured-publication-grid {
    grid-template-columns: 1fr;
  }

  .publication-item {
    grid-template-columns: 1fr;
    gap: 10px;
    padding: 22px 0;
  }

  .publication-links {
    justify-content: flex-start;
  }

  .platform-card {
    min-height: 500px;
  }

  .question-grid span {
    margin-bottom: 46px;
  }

  .question-grid article {
    min-height: 280px;
  }

  .photo-grid {
    grid-template-columns: 1fr;
    grid-auto-rows: 330px;
  }

  .photo-grid .wide {
    grid-row: span 1;
  }

  .people-grid,
  .people-grid-small {
    grid-template-columns: minmax(0, 1fr);
  }

  .person-card-featured {
    grid-template-columns: 1fr;
  }

  .person-card,
  .person-card-featured {
    max-width: 340px;
  }

  .person-card img,
  .person-card-featured img {
    width: 100%;
    height: auto;
    aspect-ratio: 4 / 5;
    min-height: 0;
  }
}

@media (prefers-reduced-motion: reduce) {
  .people-lead::before {
    animation: none;
  }
}